Peptides for men over 40

This is our canonical peptide explainer for men over 40. The peptide market is unregulated. What the published evidence actually says about BPC-157, TB-500, sermorelin, ipamorelin, semaglutide, and tirzepatide.

Quick summary

BPC-157. Strong rodent evidence for tendon and gut healing. Zero peer-reviewed human RCTs.
TB-500. Sparse controlled human evidence.
Sermorelin / Ipamorelin / CJC-1295. Growth hormone secretagogues with some evidence in GH-deficiency populations.
Semaglutide / Tirzepatide. GLP-1 agonists. Real RCT-grade evidence. FDA-approved.

Approach

Work with a licensed clinician. Use a 503B compounding pharmacy. Document baseline bloodwork and re-measure at 90 days.

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